根據【1】

VigiAccess和VigiBase的關系是：前者是后者的一個公眾接口

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http://vigiaccess.org/

例如我們想查詢covid-19 vaccine引起的眼睛相關的副作用的數據

打開后輸入：

covid-19 vaccine

然后操作如下

Distribution->Adverse drug reactions[ADRS]->Eye disorders

得到如下數據：

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• Vision blurred (27010)

• Visual impairment (18166)

• Eye pain (18060)

• Photophobia (8194)

• Eye swelling (7557)

• Ocular hyperaemia (4799)

• Diplopia (4391)

• Eye irritation (3718)

• Eye pruritus (3667)

• Lacrimation increased (3589)

• Blindness (3155)

• Ocular discomfort (2911)

• Swelling of eyelid (2711)

• Dry eye (2220)

• Periorbital swelling (1916)

• Photopsia (1905)

• Blepharospasm (1774)

• Periorbital oedema (1757)

• Eyelid oedema (1744)

• Asthenopia (1716)

• Eye haemorrhage (1634)

• Eye movement disorder (1607)

• Vitreous floaters (1526)

• Eye disorder (1456)

• Conjunctival haemorrhage (1356)

• Visual field defect (1247)

• Retinal vein occlusion (1182)

• Eyelid ptosis (1046)

• Visual acuity reduced (1014)

• Blindness unilateral (1008)

• Eye inflammation (993)

• Uveitis (884)

• Mydriasis (763)

• Blindness transient (749)

• Vitreous detachment (621)

• Retinal detachment (597)

• Retinal artery occlusion (557)

• Eye discharge (516)

• Gaze palsy (476)

• Eye oedema (460)

• Abnormal sensation in eye (436)

• Iridocyclitis (385)

• Retinal vein thrombosis (381)

• Cataract (372)

• Blepharitis (363)

• Retinal haemorrhage (360)

• Optic ischaemic neuropathy (359)

• Erythema of eyelid (355)

• Metamorphopsia (342)

• Ophthalmic vein thrombosis (336)

• Papilloedema (331)

• Eyelid function disorder (326)

• Eyelid disorder (315)

• Eyelid pain (310)

• Hypoaesthesia eye (306)

• Eyelids pruritus (295)

• Conjunctival hyperaemia (287)

• Iritis (285)

• Eyelid rash (242)

• Amaurosis fugax (237)

• Macular oedema (235)

• Foreign body sensation in eyes (230)

• Eyelid irritation (224)

• Strabismus (223)

• Retinal tear (215)

• Glaucoma (214)

• Retinal vascular thrombosis (203)

• Vitreous haemorrhage (198)

• Pupils unequal (189)

• Ophthalmoplegia (188)

• Eye haematoma (182)

• Episcleritis (159)

• Keratitis (154)

• Chorioretinopathy (153)

• Dyschromatopsia (151)

• Exophthalmos (151)

• Scleritis (148)

• Miosis (146)

• Ocular hypertension (140)

• Eye allergy (139)

• Dark circles under eyes (136)

• Pupil fixed (135)

• Periorbital pain (133)

• Macular degeneration (132)

• Ocular vascular disorder (132)

• Accommodation disorder (126)

• Scintillating scotoma (125)

• Extraocular muscle paresis (120)

• Eye infarction (120)

• Optic nerve disorder (113)

• Lagophthalmos (112)

• Conjunctivitis allergic (106)

• Eyelid haematoma (96)

• Chalazion (94)

• Myopia (92)

• Retinal artery thrombosis (92)

• Eye paraesthesia (91)

• Excessive eye blinking (90)

• Altered visual depth perception (89)

• Halo vision (88)

• Eyelid margin crusting (86)

• Amaurosis (82)

• Retinal vascular occlusion (81)

• Optic neuropathy (80)

• Sudden visual loss (77)

• Eye colour change (76)

• Acute macular neuroretinopathy (72)

• Endocrine ophthalmopathy (72)

• Retinal exudates (71)

• Maculopathy (69)

• Eczema eyelids (67)

• Eye symptom (67)

• Eyelid sensory disorder (65)

• Pupillary reflex impaired (65)

• Neovascular age-related macular degeneration (64)

• Ocular myasthenia (64)

• Retinal disorder (64)

• Chromatopsia (61)

• Retinal oedema (59)

• Visual brightness (59)

• Visual snow syndrome (58)

• Amblyopia (57)

• Conjunctival oedema (57)

• Angle closure glaucoma (56)

• Retinopathy (56)

• Ulcerative keratitis (55)

• Vitreous opacities (50)

• Retinal ischaemia (49)

• Cystoid macular oedema (48)

• Orbital oedema (48)

• Hypermetropia (45)

• Vitreous disorder (45)

• Eyelid cyst (44)

• Retinal artery embolism (43)

• Glare (41)

• Night blindness (41)

• Corneal opacity (40)

• Eye ulcer (39)

• Astigmatism (38)

• Oculogyric crisis (37)

• Orbital swelling (37)

• Pupillary disorder (37)

• Eyelid myokymia (36)

• Eyelid skin dryness (35)

• Periorbital discomfort (35)

• Xanthopsia (35)

• Vogt-Koyanagi-Harada disease (34)

• Central vision loss (33)

• Conjunctival irritation (33)

• Extraocular muscle disorder (33)

• Ophthalmic artery thrombosis (33)

• Corneal disorder (32)

• Macular hole (32)

• Retinal vasculitis (31)

• Cyanopsia (30)

• Scleral discolouration (30)

• Scleral haemorrhage (30)

• Visual acuity reduced transiently (30)

• Lid sulcus deepened (29)

• Retinal vascular disorder (29)

• Eyelid bleeding (28)

• Retinal degeneration (28)

• Corneal oedema (27)

• Dermatochalasis (27)

• Erythropsia (26)

• Lacrimation decreased (26)

• Lacrimation disorder (25)

• Optic atrophy (25)

• Optic nerve infarction (25)

• Oscillopsia (25)

• Corneal bleeding (23)

• Limbal swelling (23)

• Punctate keratitis (23)

• Binocular eye movement disorder (22)

• Eyelid exfoliation (22)

• Eyelid myoclonus (22)

• Retinal infarction (22)

• Xerophthalmia (22)

• Age-related macular degeneration (21)

• Eyelid thickening (21)

• Choroidal neovascularisation (20)

• Scleral disorder (20)

• Vitreous haze (20)

• Holmes-Adie pupil (19)

• Necrotising retinitis (19)

• Presbyopia (19)

• Dacryostenosis acquired (18)

• Meibomian gland dysfunction (18)

• Ocular rosacea (18)

• Lacrimal disorder (17)

• Orbital haematoma (17)

• Retinal pigment epitheliopathy (17)

• Corneal lesion (16)

• Growth of eyelashes (16)

• Heterophoria (16)

• Epiretinal membrane (15)

• Hyperaesthesia eye (15)

• Ocular vasculitis (15)

• Conjunctival disorder (14)

• Eyelid retraction (14)

• Lenticular opacities (14)

• Macular fibrosis (14)

• Retinal aneurysm (14)

• Ocular ischaemic syndrome (13)

• Paralytic lagophthalmos (13)

• Dry age-related macular degeneration (12)

• Idiopathic orbital inflammation (12)

• Iris adhesions (12)

• Macular detachment (12)

• Optic disc disorder (12)

• Tolosa-Hunt syndrome (12)

• Autoimmune uveitis (11)

• Corneal erosion (11)

• Iris disorder (11)

• Optic disc haemorrhage (11)

• Orbital myositis (11)

• Parophthalmia (11)

• Retinal toxicity (11)

• Vitreous degeneration (11)

• Blindness cortical (10)

• Choroiditis (10)

• Diabetic retinopathy (10)

• Retinal neovascularisation (10)

• Vitreoretinal traction syndrome (10)

• Vitritis (10)

• Chloropsia (9)

• Neurological eyelid disorder (9)

• Optic nerve sheath haemorrhage (9)

• Saccadic eye movement (9)

• Eyelash discolouration (8)

• Iris discolouration (8)

• Keratoconus (8)

• Ophthalmic artery occlusion (8)

• Opsoclonus myoclonus (8)

• Panophthalmitis (8)

• Papillophlebitis (8)

• Pinguecula (8)

• Retinopathy hypertensive (8)

• Retinoschisis (8)

• Subretinal fluid (8)

• Swollen tear duct (8)

• Bell's phenomenon (7)

• Birdshot chorioretinopathy (7)

• Cataract subcapsular (7)

• Choroidal effusion (7)

• Corneal endotheliitis (7)

• Ectropion (7)

• Eye opacity (7)

• Macular rupture (7)

• Optic discs blurred (7)

• Orbital cyst (7)

• Periorbital irritation (7)

• Refraction disorder (7)

• Retinal drusen (7)

• Rhegmatogenous retinal detachment (7)

• Scleral hyperaemia (7)

• Scleral oedema (7)

• Autoimmune eye disorder (6)

• Conjunctival pallor (6)

• Contact lens intolerance (6)

• Floppy eyelid syndrome (6)

• Fuchs' syndrome (6)

• Giant papillary conjunctivitis (6)

• Glaucomatocyclitic crises (6)

• Homonymous diplopia (6)

• Lacrimal gland enlargement (6)

• Optic nerve compression (6)

• Periorbital disorder (6)

• Retinal scar (6)

• Serous retinopathy (6)

• Arteriosclerotic retinopathy (5)

• Blepharal pigmentation (5)

• Blepharochalasis (5)

• Cataract nuclear (5)

• Charles Bonnet syndrome (5)

• Chorioretinal disorder (5)

• Conjunctival cyst (5)

• Conjunctival discolouration (5)

• Corneal irritation (5)

• Enophthalmos (5)

• Eyelid vascular disorder (5)

• Loss of visual contrast sensitivity (5)

• Macular ischaemia (5)

• Ocular sarcoidosis (5)

• Periorbital inflammation (5)

• Posterior capsule opacification (5)

• Retinal fovea disorder (5)

• Spontaneous hyphaema (5)

• Subretinal haematoma (5)

• Vitreous adhesions (5)

• Chorioretinal atrophy (4)

• Choroidal detachment (4)

• Corneal scar (4)

• Dacryoadenitis acquired (4)

• Disorder of orbit (4)

• Exudative retinopathy (4)

• Inflammation of lacrimal passage (4)

• Lens disorder (4)

• Pupillary deformity (4)

• Venous stasis retinopathy (4)

• Blepharitis allergic (3)

• Cataract cortical (3)

• Choroidal rupture (3)

• Ciliary hyperaemia (3)

• Colour blindness acquired (3)

• Computer vision syndrome (3)

• Conjunctival suffusion (3)

• Conjunctival ulcer (3)

• Corneal defect (3)

• Corneal degeneration (3)

• Corneal epithelium defect (3)

• Corneal infiltrates (3)

• Corneal perforation (3)

• Detachment of macular retinal pigment epithelium (3)

• Detachment of retinal pigment epithelium (3)

• Dysmetropsia (3)

• Exposure keratitis (3)

• Eyelash changes (3)

• Heteronymous diplopia (3)

• Hypotony of eye (3)

• Lacrimal haemorrhage (3)

• Lid lag (3)

• Macular telangiectasia (3)

• Noninfective chorioretinitis (3)

• Noninfective conjunctivitis (3)

• Ocular dysmetria (3)

• Ocular retrobulbar haemorrhage (3)

• Open angle glaucoma (3)

• Optic disc hyperaemia (3)

• Parinaud syndrome (3)

• Pigmentary glaucoma (3)

• Pseudomyopia (3)

• Pterygium (3)

• Retinal cyst (3)

• Retinal dystrophy (3)

• Retinal vessel avulsion (3)

• Vitreous haematoma (3)

• Allergic keratitis (2)

• Anterior capsule contraction (2)

• Anterior chamber flare (2)

• Anterior chamber opacity (2)

• Blindness day (2)

• Ciliary body disorder (2)

• Cogan's syndrome (2)

• Conjunctival bleb (2)

• Conjunctival opacity (2)

• Conjunctival vascular disorder (2)

• Conjunctivochalasis (2)

• Corneal endothelial cell loss (2)

• Corneal exfoliation (2)

• Delayed dark adaptation (2)

• Deposit eye (2)

• Detached Descemet's membrane (2)

• Hippus (2)

• Iris cyst (2)

• Iris neovascularisation (2)

• Keratitis interstitial (2)

• Macular pseudohole (2)

• Macular scar (2)

• Myopic chorioretinal degeneration (2)

• Necrotising scleritis (2)

• Non-infectious endophthalmitis (2)

• Ophthalmic artery aneurysm (2)

• Optic nerve cupping (2)

• Orbital haemorrhage (2)

• Orbital space occupying lesion (2)

• Retinal occlusive vasculitis (2)

• Retinal pigmentation (2)

• Retinal vein varices (2)

• Serous retinal detachment (2)

• Serpiginous choroiditis (2)

• Symblepharon (2)

• Tessellated fundus (2)

• Acute myopia (1)

• Amblyopia strabismic (1)

• Anisometropia (1)

• Anterior chamber inflammation (1)

• Aphakia (1)

• Atopic keratoconjunctivitis (1)

• Atrophy of globe (1)

• Chorioretinal folds (1)

• Choroidal haemorrhage (1)

• Choroidal infarction (1)

• Ciliary muscle spasm (1)

• Conjunctival adhesion (1)

• Conjunctival defect (1)

• Conjunctival telangiectasia (1)

• Corneal decompensation (1)

• Corneal leukoma (1)

• Corneal neovascularisation (1)

• Corneal thinning (1)

• Dellen (1)

• Diabetic retinal oedema (1)

• Disorder of globe (1)

• Disruption of the photoreceptor inner segment-outer segment (1)

• Entropion (1)

• Episcleral hyperaemia (1)

• Eversion of lacrimal punctum (1)

• Excessive ocular convergence (1)

• Exfoliation syndrome (1)

• Eye degenerative disorder (1)

• Eye muscle entrapment (1)

• Hyalosis asteroid (1)

• Immune-mediated uveitis (1)

• Intraocular haematoma (1)

• Iris bombe (1)

• Iris haemorrhage (1)

• Keratic precipitates (1)

• Keratopathy (1)

• Lacrimal structural disorder (1)

• Lens dislocation (1)

• Lid margin discharge (1)

• Macular cherry-red spots (1)

• Macular cyst (1)

• Macular opacity (1)

• Meibomianitis (1)

• Myopic traction maculopathy (1)

• Noninfective retinitis (1)

• Normal tension glaucoma (1)

• Ocular toxicity (1)

• Pingueculitis (1)

• Polypoidal choroidal vasculopathy (1)

• Pseudopapilloedema (1)

• Pupillotonia (1)

• Purtscher retinopathy (1)

• Retinal artery stenosis (1)

• Retinal depigmentation (1)

• Retinal deposits (1)

• Retinal fibrosis (1)

• Retinal pallor (1)

• Retinopathy haemorrhagic (1)

• Retinopathy proliferative (1)

• Scleral cyst (1)

• Scleritis allergic (1)

• Subconjunctival cyst (1)

• Sympathetic ophthalmia (1)

• Tear discolouration (1)

• Tractional retinal detachment (1)

• Trichiasis (1)

• Uveitic glaucoma (1)

• Vitreous cyst (1)

• Vitreous prolapse (1)

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官方說明手冊如下：

文檔正在審核中

Reference：

【1】https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051262/

總結

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